Health-related quality of life in outpatients with chronic liver disease: a cross-sectional study

Table 4 Comparison of Nottingham Health Profile—Part II among MELD score

NHP – Part II Life areas affected	MELD score*			Total (N = 252)	P-value^a
NHP – Part II Life areas affected	Class I (N = 176) n (%)	Class II (N = 76) n (%)	Class III (N = 6) n (%)	n (%)	P-value^a
Item 43—Is your present state of health causing problems with your sex life?
YES	33 (18.7)	24 (31.6)	3 (50.0)	60 (23.8)	0.037
Item 45—Is your present state of health causing problems with your vacations (summer or winter vacations, weekends away, etc.)?
YES	39 (22.1)	15 (19.7)	4 (66.6)	58 (23.0)	0.032

*MELD score using the original mathematical formula: 9.57 × loge(creatinine) + 3.78 × Loge(total bilirubin) + 11.2 × Loge(INR) + 6.43 [21]. Patients were categorized into three groups, as proposed by the Wiesner and colleagues [27], where a higher MELD score indicates a worse degree of liver disease: class I (≤ 9), class II (10–19), class III (20–29)
^aPearson’schi-squared test

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