Fig. 3

Histologic, endoscopic and clinical parameters of a representative FMT responder (E), non-responder (N), and placebo subject (Y) before and after treatment. Hematoxylin–eosin staining of intestinal mucosa highlight acute and chronic changes and are accompanied by Geboes score (0, structural change only; 1, chronic inflammation; 2, lamina propria neutrophils; 3, neutrophils in epithelium; 4, crypt destruction; and 5, erosions or ulcers), 2x, insets at 20x, scale bar, 50 µm; UCEIS, Ulcerative Colitis Endoscopic Index of Severity; fecal calprotectin (mcg/g), and IBDQ, inflammatory bowel disease questionnaire (scale ranging from 32 (worst) to 224 (best))