Table 1 Baseline demographic and clinicopathological characteristics of patients with SRC vs. non-SRC
From: Clinicopathological characteristics and prognosis of signet ring cell carcinoma of the gallbladder
Parameters | SRC (n = 377) | Non-SRC (n = 22,404) | P Value |
|---|---|---|---|
Age, years | |||
< 60 | 83 (22.0%) | 6954 (31.0%) | < 0.001 |
≥ 60 | 294 (78.0%) | 15,450 (69.0%) | |
Sex | |||
Male | 88 (23.3%) | 6625 (29.6%) | 0.009 |
Female | 289 (76.7%) | 15,779 (70.4%) | |
Race | |||
White | 291 (77.2%) | 17,781 (79.4%) | 0.535 |
Black | 44 (11.7%) | 2264 (10.1%) | |
Other | 42 (11.1%) | 2359 (10.5%) | |
Clinical T-stage | |||
T1–T2 | 87 (23.1%) | 4750 (21.2%) | < 0.001 |
T3–T4 | 121 (32.1%) | 5248 (23.4%) | |
Unknown | 169 (44.8%) | 12,406 (55.4%) | |
Lymph node metastasis | |||
No | 115 (30.5%) | 6802 (30.4%) | < 0.001 |
Yes | 91 (24.1%) | 3158 (14.1%) | |
Unknown | 171 (45.4%) | 12,444 (55.5%) | |
Distant metastasis | |||
No | 133 (35.3%) | 6693 (29.9%) | < 0.001 |
Yes | 93 (24.7%) | 4445 (19.8%) | |
Unknown | 151 (40.1%) | 11,266 (50.3%) | |
AJCC stage | |||
I–II | 118 (31.3%) | 5811 (25.9%) | < 0.001 |
III–IV | 105 (27.9%) | 5054 (22.6%) | |
Unknown | 154 (40.8%) | 11,539 (51.5%) | |
Histologic grade | |||
Well-moderate | 23 (6.1%) | 8629 (38.5%) | < 0.001 |
Poor-undifferentiated | 269 (71.4%) | 6588 (29.4%) | |
Unknown | 85 (22.5%) | 7187 (32.1%) | |
Surgery | |||
Yes | 246 (65.3%) | 7138 (31.9%) | < 0.001 |
No | 66 (17.5%) | 3556 (15.9%) | |
Unknown | 65 (17.2%) | 11,710 (52.3%) | |
Radiotherapy | |||
Yes | 52 (13.8%) | 2354 (10.5%) | 0.04 |
No | 325 (86.2%) | 20,050 (89.5%) | |
Chemotherapy | |||
Yes | 125 (33.2%) | 6006 (26.8%) | 0.006 |
No | 252 (66.8%) | 16,398 (73.2%) | |
Year of diagnosis | |||
1975–2009 | 249 (66.0%) | 15,676 (70.0%) | 0.100 |
2010–2016 | 128 (34.0%) | 6728 (30.0%) | |
Marital status | |||
Married | 183 (48.5%) | 11,854 (52.9%) | 0.092 |
Unmarried | 194 (51.5%) | 10,550 (47.1%) |