Table 4 Risk factors for persistent/recurrent anemia (group C)

Female sex

1.32 (0.97–1.79)

0.0804

0.78 (0.56–1.10)

0.1555

CD diagnosis

1.59 (1.16–2.19)

0.0044

0.77 (0.54–1.10)

0.1519

Median IBD duration

1.0304 (1.01–1.05)

0.0100

1.03 (1.00–1.05)

0.0259

Median diagnosis age

0.9971 (0.99–1.01)

0.5563

Active smokers

1.04 (0.75–1.45)

0.8113

CRP > 3 mg/dl

1.11 (0.79–1.56)

0.5512

Extensive colitis

1.28 (0.76–2.14)

0.3568

Penetrating or stricturing CD

2.07 (1.40–3.07)

0.0003

Ileocolonic

1.09 (0.74–1.61)

0.6464

EIMs

1.82 (1.33–2.49)

0.0002

1.79 (1.27–2.52)

0.0008

Major disease surgeries

2.15 (1.43–3.23)

0.0002

1.73 (1.07–2.78)

0.0257

IBD hospitalizations^a

2.39 (1.56–3.66)

0.0001

1.96 (1.25–3.09)

0.0035

Immmunomodulators

1.20 (0.89–1.64)

0.2346

Anti-TNF any time

1.53 (1.11–2.12)

0.0090

0.79 (0.55–1.14)

0.2062

Other biologics at any time

1.48 (0.82–2.68)

0.1944