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Table 3 Pathological evaluation of treatment in pigs A and B

From: Endoscopic resection combined with the Cryoballoon focal ablation system in the porcine normal esophagus: a preclinical study

 

Lesion number

Treatment

Time to euthanasia from treatment (days)

Pathological evaluation

Size of EMR ulcer (mm)

Depth of tissue damage

Findings of ablation damage

Pig A

#1

EMR + CbFAS

32

 

Submucosa

Fibrosis

#2

   

Submucosa

Fibrosis

#3

 

4

33 × 14

Muscle layer (inner circular layer)

Necrosis

#4

  

22 × 10

Adventitia

Necrosis

Pig B

#5

CbFAS for EMR scar

4

 

Muscle layer (inner circular layer)

Necrosis

#6

   

Submucosa

Necrosis

#7

CbFAS alone

  

Adventitia

Necrosis

#8

   

Submucosa

Necrosis

Pig C

#9

EMR for CbFAS scar

4

18 × 12

Submucosa

 

#10

  

20 × 10

Submucosa

 

#11

EMR

 

25 × 10

Submucosa

 

#12

  

32 × 15

Submucosa

 
  1. EMR, endoscopic mucosal resection; CbFAS, Cryoballoon focal ablation system
  2. EMR + CbFAS, simultaneous use of ER and CbFAS