Table 5 Analysis of prognostic factors in the younger group
Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | |
Sex (male/female) | 1.09 (0.77–1.54) | 0.63 | ||
PS score of 2–4 | 3.49 (1.86–6.54) | < 0.0001 | 1.16 (0.57–2.35) | 0.68 |
Tumor located on the right side | 1.02 (0.72–1.44) | 0.92 | ||
Albumin level ≤ 3.5 g/dL | 1.60 (1.13–2.26) | 0.008 | 1.61 (1.13–2.28) | 0.008 |
BMI ≤ 18.5 | 1.08 (0.62–1.88) | 0.79 | ||
PNI ≤ 35 | 1.38 (0.84–2.27) | 0.21 | ||
Creatinine level ≥ 1.5 mg/dL | 0.62 (0.25–1.53) | 0.30 | ||
CEA level ≥ 5 ng/mL | 1.35 (0.89–2.04) | 0.16 | ||
RAS mutation type | 1.06 (0.72–1.54) | 0.78 | ||
Poorly differentiated cancer or signet-ring cell carcinoma | 0.74 (0.38–1.46) | 0.38 | ||
Resection of primary tumor | 0.45 (0.31–0.64) | < 0.0001 | 0.44 (0.31–0.64) | < 0.0001 |
Chemotherapy | 0.23 (0.14–0.38) | < 0.0002 | 0.22 (0.13–0.37) | < 0.0001 |