Table 1 Baseline Characteristics of patients diagnosed with mCRC, separated according to those aged < 80 and ≥ 80 years old
Variable | Younger group (n = 217) | Super elderly group (n = 43) | |
|---|---|---|---|
n or median (range) | n or median (range) | P | |
Age(years) | 68 (27–79) | 83 (80–93) | < 0.0001 |
Male sex (%) | 135 (62%) | 21 (49%) | 0.11 |
PS score of 0–1 | 197 (91%) | 28 (65%) | < 0.0001 |
Primary site | 0.32 | ||
Colon | 187 (86%) | 40 (93%) | |
Rectum | 30 (14%) | 3 (7%) | |
Tumor located in the right-side | 83 (38%) | 11 (26%) | 0.12 |
Site of metastases | |||
Liver only | 80 (37%) | 15 (35%) | 0.86 |
Lung only | 19 (9%) | 7 (16%) | 0.16 |
Liver and lung | 35 (16%) | 7 (16%) | 1 |
Other | 88 (41%) | 14 (33%) | 0.39 |
Albumin level (g/dL) | 3.8 | 3.7 | 0.21 |
BMI | 22.9 | 21.4 | 0.03 |
PNI | 46.2 | 42.6 | 0.04 |
Creatinine level (mg/dL) | 0.77 | 0.84 | 0.1 |
CEA level (ng/mL) | 20.1 | 11.4 | 0.04 |
RAS mutation type | 78 (46%) | 7 (54%) | 0.58 |
Poorly differentiated cancer or signet-ring cell carcinoma | 14 (6%) | 9 (21%) | < 0.0001 |