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Table 4 Multivariable analysis of predictors for recipient overall survival

From: Impact of donor age on liver transplant outcomes in patients with hepatocellular carcinoma: analysis of the SRTR database

 

HR (95% CI)

P value

Donor age (reference Group I)

 

 < 0.001

 Group II

1.087 (0.979–1.208)

0.119

 Group III

1.124 (1.015–1.246)

0.025

 Group IV

1.395 (1.215–1.602)

 < 0.001

Recipient age

1.021 (1.014–1.027)

 < 0.001

Recipient race (reference White)

 

0.013

 Black or African American

1.141 (1–1.301)

0.050

 Asian

0.878 (0.726–1.062)

0.181

 Hispanic/Latino

0.882 (0.783–0.993)

0.038

 Other

1.178 (0.85–1.633)

0.326

Underlying liver diseases (reverence HCV)

 

0.011

 HBV

0.724 (0.596–0.879)

0.001

 Alcoholic liver diseases

0.935 (0.803–1.088)

0.383

 NASH

0.878 (0.748–1.029)

0.108

 Other

0.992 (0.864–1.138)

0.904

MELD

1.013 (1.006–1.019)

 < 0.001

Recipient serum creatinine (mg/dl)

1.051 (1.008–1.095)

0.019

Sum of tumor diameters (cm)

1.052 (1.033–1.072)

 < 0.001

AFP (≥ 400 ng/ml vs. < 400 ng/ml)

1.993 (1.648–2.412)

 < 0.001

Tacrolimus maintenance at discharge

0.911 (0.835–0.994)

0.035

Steroids maintenance at discharge

0.762 (0.696–0.835)

 < 0.001

  1. AFP, α-fetoprotein; HBV, hepatitis B virus; HCV, hepatitis C virus; MELD, model for end-stage liver disease; NASH, nonalcoholic steatohepatitis