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Table 4 Perioperative parameters and response information stratified by post-NACT CTM score after NACT in 533 patients

From: Combination of tumor markers predicts progression and pathological response in patients with locally advanced gastric cancer after neoadjuvant chemotherapy treatment

 

All patients

CTM 0 (N = 140)

CTM 1 (N = 233)

CTM 2 (N = 116)

CTM 3 (N = 44)

P

Hospital stay (days)*

10 (9, 13)

10 (8, 13)

10 (9, 13)

11 (9, 14)

10 (9.5, 13.5)

0.137

Operative time (min)*

201 (174, 241)

199 (170, 233.5)

200 (172, 240)

203.5 (178, 245.5)

226 (179.5, 271)

0.072

Blood loss (ml)*

100 (100, 200)

100 (99.5, 150)

100 (100, 200)

100 (100, 200)

100 (100, 200)

0.064

The number of resected lymph nodes*

31 (23,40.5)

30.5 (22, 40)

30 (23, 40)

31 (24, 39.5)

31 (28, 40.5)

0.645

The number of positive lymph nodes*

1 (0, 5)

0 (0, 3)

1 (0, 4)

2 (0, 8)

4 (0, 11)

 < 0.001

Clavien–Dindo

     

0.104

 0–II

455 (85.37)

120 (85.71)

206 (88.41)

96 (82.76)

33 (75.00)

 

 III-IV

78 (14.63)

20 (14.29)

27 (11.59)

20 (17.24)

11 (25.00)

 

LVI

177 (33.21)

36 (25.71)

68 (29.18)

56 (48.28)

17 (38.64)

0.001

ypT0

39 (7.32)

15 (10.71)

19 (8.15)

3 (2.59)

2 (4.55)

0.062†

ypN0

233 (43.71)

75 (53.57)

110 (47.21)

35 (30.17)

13 (29.55)

 < 0.001

pCR

34 (6.38)

14 (10.00)

16 (6.87)

2 (1.72)

2 (4.55)

0.039†

  1. Categorical variables are summarized with counts, percentage and P values based on chi-square tests; Continuous variables are summarized with median, IQR, and P values for Kruskal–Wallis test; CTM, combination of tumor markers; LVI, lymph vascular invasion; pCR, pathological complete response
  2. †P value for Fisher’s exact test