Hybrid endoscopic submucosal dissection: An alternative resection modality for large laterally spreading tumors in the cecum?

Table 1 Baseline characteristics

	ESD (n = 27)	Hybrid ESD (n = 35)	P-value
Patients
Sex (male/female)	8/19	13/22	0.535
Age, median (range), years	63 (34–75)	61 (39–82)	0.955
BMI, median (range)	23.7 (19.1–31.1)	24.4 (16.9–33.2)	0.422
Lesions
Size, median (range), mm	25 (20–62)	23 (20–42)	0.104
Endoscopic type, n (%)			0.464
LST-G-H	10 (37.0%)	9 (25.7%)
LST-G-NM	14 (51.9%)	18 (51.4%)
LST-NG-FE	3 (11.1%)	6 (17.2%)
LST-NG-PD	0 (0.0%)	2 (5.7%)
Appendiceal orifice or Ileocecal valve involvement, n (%)			0.142
Appendiceal orifice	5 (18.5%)	4 (11.4%)
Ileocecal valve	5 (18.5%)	1 (2.9%)
Both Ileocecal valve and appendiceal orifice	1 (3.7%)	2 (5.7%)
Histopathology, n (%)			0.517
Adenoma with low grade dysplasia	17 (63.0%)	27 (77.1%)
Adenoma with high grade dysplasia	7 (25.9%)	5 (14.3%)
Intramucosal cancer	2 (7.4%)	1 (2.9%)
Submucosal invasion cancer	1 (3.7%)	2 (5.7%)
Antithrombotic medications^b, n (%)			0.788
Antiplatelet agents	2 (7.4%)	2 (5.7%)
Anticoagulants	0 (0.0%)	0 (0.0%)
Submucosal fibrosis, n (%)			0.033^a
F0	19 (70.4%)	13 (37.1%)
F1	6 (22.2%)	15 (42.9%)
F2	2 (7.4%)	7 (20.0%)

ESD endoscopic submucosal dissection, LST-G laterally spreading tumors-granular type, LST-NG laterally spreading tumors-nongranular type, LST-G-H laterally spreading tumors-granular-homogeneous type, LST-G-NM laterally spreading tumors-granular-nodular mixed types, LST-NG-FE laterally spreading tumors-nongranular-flat elevated type, LST-NG-PD laterally spreading tumors-nongranular-pseudodepressed type
^aP < 0.05
^bAll patients stopped the medicine for 7 days before the procedure

ISSN: 1471-230X