Comparison of preoperative two-dimensional shear wave elastography, indocyanine green clearance test and biomarkers for post hepatectomy liver failure prediction in patients with hepatocellular carcinoma

Table 2 Parameters of development cohort

Variable	All patients (n = 150)	Patients without PHLF (n = 133)	Patients with PHLF (n = 17)	P value
LSV (kPa)	9.0 (6.9, 11.9)	8.5 (6.8, 11.0)	13.0 (10.5, 16.0)	< 0.0001
ICG-R15 (%)	5.4 (3.4, 7.2)	5.2 (3.4, 7.1)	6.4 (4.0, 8.8)	0.009
ALBI scores	− 2.8 (− 3.0, − 2.5)	− 2.8 (− 3.0, − 2.6)	− 2.5 (− 2.8, − 2.2)	0.012
APRI	0.63 (0.41, 1.16)	0.62 (0.38, 1.14)	0.62 (0.50, 1.29)	0.488
FIB-4	9.17 (6.81, 11.55)	9.17 (6.79, 11.60)	8.88 (6.76, 11.30)	0.704

Data were described as medians (interquartile range). Statistical analysis was conducted for comparison between patients with and without post hepatectomy liver failure (PHLF) groups. LSV = liver stiffness value; ICG-R15 = indocyanine green retention rate at 15 min; ALBI = albumin-bilirubin; APRI = aspartate aminotransferase–platelet ratio index; FIB-4 = Fibrosis-4

ISSN: 1471-230X