Table 2 Summary of sensitivity and specificity of surveillance methods for early stage HCC detection in patients with cirrhosis
Surveillance assay | Sensitivity | Specificity |
|---|---|---|
Test study | ||
HCCBloodTest | 76.7% (CI 95 64.6–85.6) | 64.1% (CI 95: 54.5–72.7) |
NGS panel | 57% (44–68) | 97% (92–99) |
AFP (20 ng) | 36% (25–48) | 95% (89–98) |
Post hoc analyses | ||
AFP | 31% (20–43) | 97% (92–99) |
mSEPT9 + AFP | 42% (31–55) | 97% (92–99) |
NGS panel + AFP | 68% (55–78) | 97% (92–99) |