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Table 1 Patient cohort characteristics of all enrolled patients including two that did not meet inclusion criteria for the final analysis

From: Plasma cell free DNA methylation markers for hepatocellular carcinoma surveillance in patients with cirrhosis: a case control study

Variable

Patient without HCC (n = 104)

Patients with HCC (n = 61)

 

Continuous

Median (min, max)

Median (min, max)

p value (test method)

Age (years)

57 (28–74)

64 (34–89)

< 0.001 (Wilcox)

Number of HCC nodules

1 (1–5)

Size of largest HCC nodule (mm)

27 (7–118)

Categorical

Count (%)

Count (%)

 

Male sex

44 (42.3)

43 (70.5)

< 0.001 (Fisher)

Child-class

  

0.32 (Fisher)

 A

60 (57.7)

41 (67.2)

 

 B

43 (41.3)

20 (32.8)

 

 C (excluded)

1 (1.0)

 

Etiology of cirrhosis

  

0.17 (Chi-square)

 ALD

26 (25.0)

15 (24.6)

 

 HBV

2 (1.9)

4 (6.6)

 

 HCV

20 (19.2)

18 (29.5)

 

 NASH

33 (31.7)

17 (27.9)

 

 Other

23 (22.1)

7 (11.5)

 

BCLC stage

 Stage 0

10 (16.4)

 Stage A

39 (63.9)

 Stage B

11 (18.0)

 Stage D (excluded)

 

1 (1.6)