Fig. 1

Study selection process: Overall, a total of 3277 articles were identified using the above mentioned search strategy from the pre-specified databases. 1577 studies were removed as duplicates and the remaining 1700 studies were screened using the pre-specified inclusion and exclusion criteria. After title and abstract screening, 1545 studies were deemed irrelevant, and the remaining 155 articles were reviewed by full-text. 15 studies were selected for inclusion of the systematic review. Additional 9 articles/product monographs were identified outside of the search strategy and included for the review