Table 3 Factors associated with HGIN and ESCC in patients diagnosed as negative/indefinite for neoplasia or LGIN on biopsy
Variables | Total (n = 30) | Final histology | p value | |
|---|---|---|---|---|
No-IN/LGIN (n = 13) | HGIN/ESCC (n = 17) | |||
Age(years) | Â | Â | Â | 0.465 |
 < 60 | 12 (40) | 4 (30.8) | 8 (47.1) |  |
 ≥ 60 | 18 (60) | 9 (69.2) | 9 (52.9) |  |
Sex | Â | Â | Â | 0.264 |
 Male | 18 (60) | 6 (46.2) | 12 (70.6) |  |
 Female | 12 (40) | 7 (53.8) | 5 (29.4) |  |
Lesion size (mm) | Â | Â | Â | 0.002 |
 < 10 | 11 (36.7) | 9 (69.2) | 2 (11.8) |  |
 ≥ 10 | 19 (63.3) | 4 (30.8) | 15 (88.2) |  |
Location | Â | Â | Â | 0.971 |
 Upper esophagus | 2 (6.7) | 1 (7.7) | 1 (5.9) |  |
 Middle esophagus | 23 (76.7) | 10 (76.9) | 13 (76.5) |  |
 Lower esophagus | 5 (16.7) | 2 (15.4) | 3 (17.6) |  |
Color under white light endoscopy | Â | Â | Â | 0.167 |
 Reddish | 18 (60.0) | 6 (46.2) | 12 (70.6) |  |
 Whitish | 7 (23.3) | 3 (23.1) | 4 (23.5) |  |
 No obvious change | 5 (16.7) | 4 (30.7) | 1 (5.9) |  |
Gross type | Â | Â | Â | 0.379 |
 Elevated | 1 (3.3) | 0 (0) | 1 (5.9) |  |
 Flat | 25 (83.4) | 12 (92.3) | 13 (76.5) |  |
 Depressed | 4 (13.3) | 1 (7.7) | 3 (17.6) |  |
Pink color sign | Â | Â | Â | 0.613 |
 Yes | 4 (13.3) | 1 (7.7) | 3 (17.6) |  |
 No | 26 (86.7) | 12 (92.3) | 14 (82.4) |  |
IPCL |  |  |  | < 0.001 |
 Type A | 10 (33.3) | 10 (76.9) | 0 (0) |  |
 Type B | 20 (66.7) | 3 (23.1) | 17 (100) |  |
Brownish color background | Â | Â | Â | Â 0.138 |
 Yes | 17 (56.7) | 5 (38.5) | 12 (70.6) |  |
 No | 13 (43.3) | 8 (61.5) | 5 (29.4) |  |
Number of biopsies |  |  |  | – |
 1 | 30 (100) | 13 (100) | 17 (100) |  |
 ≥ 2 | 0 (0) | 0 (0) | 0 (0) |  |