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Table 2 Acid-neutralizing activity of the calcium/magnesium carbonate-based antacid versus placebo (n = 6)

From: Onset of acid-neutralizing action of a calcium/magnesium carbonate-based antacid using an artificial stomach model: an in vitro evaluation

pH parameter

Placebo

Antacid

Time to reach pH:

3.0

–

00:00:40 ± 00:00:02

3.5

–

00:00:53 ± 00:00:02

4.0

–

00:01:13 ± 00:00:04

4.5

–

00:01:54 ± 00:00:12

Maximum pH

1.28 ± 0.10

5.24 ± 0.07

Duration of maximum pH

00:13:05 ± 00:07:20

00:09:56 ± 00:00:44

  1. Results presented as average ± standard deviation (units of time: hours:minutes:seconds)
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BMC Gastroenterology

ISSN: 1471-230X

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