A: All patients | |||||||
---|---|---|---|---|---|---|---|
2-year mortality | Univariate Cox regression | Multivariate Cox regression | |||||
HR | CI (95%) | p value | HR | CI (95%) | p value | ||
Age (≥ 50) | 4.341 | 1.565–12.040 | 0.005 | 2.669 | 0.945–7.541 | 0.064 | |
Sex (female) | 0.98 | 0.569–1.688 | 0.941 |  |  |  | |
Alcoholic etiology | 1.341 | 0.762–2.358 | 0.309 |  |  |  | |
MELD (5-point increase) | 2.029 | 1.482–2.776 | < 0.001 | 1.758 | 1.201–2.572 | 0.004 | |
Child–Pugh | A | Reference | |||||
B | 2.936 | 1.167–5.223 | < 0.001 | 2.617 | 1.408–4.861 | 0.002 | |
C | 4.834 | 1.817–12.857 | 0.002 | 1.950 | 0.625–6.079 | 0.250 | |
Decompensated state | 2.021 | 1.109–3.683 | 0.022 | 0.969 | 0.428–2.194 | 0.940 | |
Presence of comorbidity | 2.244 | 1.245–4.046 | 0.007 | 1.270 | 0.665–2.429 | 0.469 | |
Presence of HCC | 5.642 | 3.064–10.388 | < 0.001 | 8.827 | 4.423–17.618 | < 0.001 | |
CRP (≥ 10) | 3.021 | 1.674–5.450 | < 0.001 | 1.567 | 0.799–3.076 | 0.191 | |
Anemia | 1.969 | 1.141–3.400 | 0.015 | 1.420 | 0.810–2.490 | 0.221 | |
High Ferritin | 2.209 | 1.269–3.844 | 0.005 | 2.143 | 1.174–3.910 | 0.013 |
B: Compensated patients | ||||||
---|---|---|---|---|---|---|
2-year mortality | Univariate Cox regression | Multivariate Cox regression | ||||
HR | CI (95%) | p value | HR | CI (95%) | p value | |
Age (≥ 50) | 2.886 | 0.651–12.791 | 0.163 |  |  |  |
Sex (female) | 0.583 | 0.207–1.638 | 0.306 |  |  |  |
Alcoholic etiology | 1.235 | 0.439–3.469 | 0.689 |  |  |  |
MELD (5-point increase) | 2.135 | 0.936–4.869 | 0.071 | 2.595 | 1.088–6.188 | 0.032 |
Child–Pugh B | 0.047 | 0.000–5234 | 0.606 |  |  |  |
Presence of comorbidity | 1.947 | 0.692–5.476 | 0.207 |  |  |  |
Presence of HCC | 4.691 | 1.593–13.809 | 0.005 | 9.211 | 2.854–29.731 | < 0.001 |
CRP (≥ 10) | 1.789 | 0.404–7.929 | 0.444 |  |  |  |
Anemia | 2.506 | 0.890–7.057 | 0.082 | 1.333 | 0.424–4.184 | 0.623 |
High Ferritin | 2.903 | 1.052–8.012 | 0.040 | 4.367 | 1.466–13.009 | 0.008 |
C: Decompensated patients | |||||||
---|---|---|---|---|---|---|---|
2-year mortality | Univariate Cox regression | Multivariate Cox regression | |||||
HR | CI (95%) | p value | HR | CI (95%) | p value | ||
Age (≥ 50) | 5.303 | 1.275–22.051 | 0.022 | 2.608 | 0.602–11.308 | 0.200 | |
Sex (female) | 1.317 | 0.691–2.509 | 0.403 |  |  |  | |
Alcoholic etiology | 0.964 | 0.466–1.993 | 0.921 |  |  |  | |
MELD (5-point increase) | 1.833 | 1.271–2.643 | 0.001 | 1.639 | 1.096–2.452 | 0.016 | |
Child–Pugh | A | Reference | |||||
B | 3.940 | 1.620–9.582 | 0.002 | 2.514 | 1.003–6.301 | 0.049 | |
C | 6.024 | 1.831–19.815 | 0.003 | 1.888 | 0.493–7.227 | 0.353 | |
Presence of comorbidity | 2.196 | 1.063–4.538 | 0.034 | 1.479 | 0.657–3.327 | 0.344 | |
Presence of HCC | 8.225 | 3.810–17.756 | < 0.001 | 8.058 | 3.461–18.759 | < 0.001 | |
Presence of ascites | 3.461 | 1.518–7.891 | 0.003 | 1.526 | 0.589–3.953 | 0.384 | |
Previous VB | 0.212 | 0.088–0.51 | 0.001 | 0.310 | 0.126–0.762 | 0.011 | |
Previous BI | 1.532 | 0.800–2.937 | 0.198 |  |  |  | |
CRP (≥ 10) | 2.922 | 1.500–5.693 | 0.002 | 2.192 | 1.086–4.427 | 0.029 | |
Anemia | 1.432 | 0.743–2.762 | 0.284 |  |  |  | |
High Ferritin | 2.251 | 1.146–4.424 | 0.019 | 1.016 | 0.436–2.371 | 0.970 |