Table 3 Results of each questionnaire on gastrointestinal symptoms

Gastrointestinal symptoms

Modified Frequency Scale for the Symptoms of GERD (mFSSG)

 Total score

21.0

[17.0, 30.5]

16.0

[6.0, 19.0]

− 34.7

[− 66.8, + 4.2]

.004

 Reflux score

8.0

[5.5, 14.5]

6.0

[3.3, 8.8]

− 38.8

[− 62.7, − 3.6]

.011

 Dyspepsia score

12.0

[9.0, 17.8]

8.5

[2.0, 13.0]

− 44.1

[− 79.2, − 3.6]

.005

Gastrointestinal Symptom Rating Scale (GSRS)

 Total Score

44.0

[37.5, 54.8]

31.0

[22.0, 40.5]

− 31.4

[− 46.0, − 22.3]

.005

 Reflux

6.5

[3.5, 9.8]

4.0

[2.0, 6.0]

− 36.7

[− 57.5, 0]

.012

 Abdominal pain

11.0

[6.3, 14.8]

5.0

[3.0, 9.0]

− 45.0

[− 66.7, − 11.8]

.002

 Indigestion

11.0

[8.3, 15.8]

8.0

[5.3, 10.8]

− 34.5

[− 41.6, − 16.0]

.004

 Diarrhea

7.0

[3.0, 9.8]

6.5

[4.0, 8.8]

0

[− 29.5, 0]

.199

 Constipation

7.5

[5.3, 11.0]

6.0

[4.0, 8.8]

− 26.2

[− 40.0, − 2.3]

.020

 Constipation scoring system (CSS)

6.0

[4.3, 10.8]

6.0

[3.0, 9.5]

− 10.0

[− 39.4, + 6.2]

.166

Japanese Version of the Patient Assessment of Constipation Quality of Life (JPAC− QOL)

 Total score

26.0

[17.5, 56.8]

15.5

[9.0, 42.5]

− 30.4

[− 65.3, 0]

.005

 Physical discomfort

6.0

[4.3, 8.0]

3.5

[2.3, 8.0]

− 41.7

[− 50.0, 0]

.009

 Psychological discomfort

5.5

[4.0, 10.8]

6.0

[2.0, 10.8]

− 18.3

[− 50.0, 0]

.030

 Worries and concerns

9.5

[6.0, 20.8]

5.0

[0.3, 18.3]

− 33.1

[− 98.1, − 1.5]

.009

 Satisfaction

7.0

[2.0, 13.8]

5.0

[0, 7.0]

− 42.8

[− 92.9, − 1.9]

.012