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Table 3 The individual and combined associations of hyperuricemia and obesity with the severity of NAFLD

From: Obesity interacts with hyperuricemia on the severity of non-alcoholic fatty liver disease

 

Serious hepatic steatosis, n (%)

Elevated ALT, n (%)

Intermediate to high risk of advanced fibrosis, n (%)

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

Group A

1

 

1

 

1

 

Group B

1.53 (0.64–3.65)

0.343

2.13 (0.77–5.93)

0.148

0.61 (0.15–2.42)

0.478

Group C

3.32 (2.09–5.28)

< 0.001

1.88 (1.09–3.23)

0.022

2.13 (1.09–4.15)

0.027

Group D

6.32 (3.36–11.89)

< 0.001

4.01 (2.11–7.63)

< 0.001

4.36 (1.94–9.76)

< 0.001

  1. Adjusted for age, gender, TG, low HDL-C, elevated fasting glucose, elevated blood pressure. Group A: normo-uricemia and non-obesity. Group B: hyperuricemia and non-obesity. Group C: normo-uricemia and obesity. Group D: hyperuricemia and obesity