Associations between disease activity, social support and health-related quality of life in patients with inflammatory bowel diseases: the mediating role of psychological symptoms

Table 3 Mediation effect of DAI-HAD-HRQoL, and Social Support-HAD-HRQoL by PROCESS

Effect	Coeff.	t/Z	P	LLCI	ULCL
Mediation analysis 1: DAI-HAD-HRQoL
Total effect	−5.54	−13.21	0.000^**	−6.37	−4.71
Direct effect	−2.74	−7.14	0.000^**	−3.49	−1.98
Indirect effect	−2.81	−7.81	0.000^**	−3.63	−2.14
a1	1.10	9.97	0.000^**	0.89	1.32
b	−2.54	−12.62	0.000^**	−2.94	−2.15
Mediation analysis 2: Social Support-HAD-HRQoL
Total effect	1.38	4.90	0.000^**	0.82	1.93
Direct effect	0.18	0.79	0.428	−0.27	0.64
Indirect effect	1.20	5.65	0.000^**	0.81	1.68
a2	−0.47	−6.34	0.000^**	−0.62	− 0.32
b	−2.54	−12.62	0.000^**	−2.94	−2.15

^**P < 0.01Abbreviations: DAI Disease activity indices, HAD Hospital anxiety and depression, HRQoL Health related quality of life, LLCI Lower level confidence interval, ULCL Upper level confidence interval

ISSN: 1471-230X