Table 3 Regression results predicting work and activity impairment in the US (a) and EU5 (b)

b

95% CI

P

b

95% CI

P

b

95% CI

P

b

95% CI

P

Intercept

4.308

2.693, 5.923

< 0.001

3.679

2.182, 5.177

< 0.001

4.077

2.573, 5.580

< 0.001

3.612

2.722, 4.502

< 0.001

Age

−0.002

−0.031, 0.026

0.864

− 0.004

− 0.020, 0.012

0.617

− 0.002

− 0.019, 0.014

0.782

− 0.002

− 0.014, 0.010

0.770

Female

0.587

0.111, 1.063

0.016

−0.047

− 0.399, 0.305

0.794

−0.090

− 0.450, 0.270

0.624

0.097

−0.180, 0.374

0.492

BMI

−0.019

−0.089, 0.051

0.595

0.007

−0.042, 0.055

0.790

0.001

− 0.047, 0.048

0.983

0.008

−0.020, 0.037

0.568

 Current smoker^a

–

–

–

–

–

–

–

–

–

–

–

–

 Former smoker

− 0.460

−1.214, 0.294

0.231

0.071

− 0.610, 0.752

0.838

− 0.130

− 0.870, 0.609

0.730

− 0.179

− 0.712, 0.354

0.511

 Never smoker

−0.401

−1.115, 0.313

0.271

−0.156

− 0.826, 0.513

0.648

− 0.348

− 1.074, 0.378

0.348

− 0.164

− 0.666, 0.338

0.522

CCI

− 0.137

− 0.636, 0.361

0.589

0.014

−0.368, 0.396

0.942

0.053

−0.335, 0.440

0.790

0.216

−0.028, 0.460

0.083

Years diagnosed

−0.139

− 0.203, − 0.075

< 0.001

−0.030

− 0.064, 0.004

0.086

− 0.033

−0.068, 0.002

0.066

−0.024

− 0.049, 0.001

0.057

 Active disease^a

–

–

–

–

–

–

–

–

–

–

–

–

 Remission

−0.906

−1.456, − 0.356

0.001

− 0.889

−1.247, − 0.531

< 0.001

−0.967

− 1.340, − 0.593

< 0.001

−0.730

−1.028, − 0.431

< 0.001

 Deep remission

0.964

−0.408, 2.336

0.169

−1.436

−2.078, − 0.793

< 0.001

− 1.447

− 2.091, − 0.804

< 0.001

−1.449

− 1.922, − 0.977

< 0.001

b

95% CI

P

b

95% CI

P

b

95% CI

P

b

95% CI

P

Intercept

4.307

3.027, 5.586

< 0.001

3.838

3.099, 4.578

< 0.001

4.039

3.256, 4.822

0.000

3.904

3.404, 4.404

< 0.001

 France^a

–

–

–

–

–

–

–

–

–

–

–

–

 Germany

−0.184

− 0.613, 0.245

0.400

− 0.472

− 0.708, − 0.236

< 0.001

−0.283

− 0.542, − 0.025

0.031

−0.297

− 0.479, − 0.116

0.001

 Italy

− 1.415

−2.236, − 0.594

0.001

− 0.276

−0.887, 0.334

0.375

−0.040

− 0.665, 0.585

0.900

− 0.302

− 0.662, 0.059

0.101

 Spain

−0.638

− 1.116, − 0.160

0.009

− 0.054

−0.360, 0.253

0.732

0.083

−0.239, 0.406

0.613

−0.137

−0.350, 0.076

0.208

 UK

−0.366

−0.972, 0.240

0.236

−0.435

− 0.884, 0.014

0.058

− 0.328

−0.794, 0.139

0.169

0.104

−0.213, 0.421

0.520

Age

0.004

−0.013, 0.021

0.649

0.007

−0.004, 0.019

0.191

0.005

−0.007, 0.016

0.416

0.006

−0.001, 0.012

0.074

Female

−0.053

−0.395, 0.289

0.762

0.105

−0.100, 0.310

0.317

0.097

−0.129, 0.323

0.400

0.052

−0.102, 0.205

0.511

BMI

0.006

−0.037, 0.050

0.777

0.003

−0.021, 0.028

0.789

0.002

−0.024, 0.027

0.896

−0.004

−0.022, 0.013

0.631

 Current smoker^a

–

–

–

–

–

–

–

–

–

–

–

–

 Former smoker

−0.055

−0.523, 0.414

0.819

0.203

−0.077, 0.483

0.155

0.240

−0.071, 0.551

0.130

0.207

−0.016, 0.430

0.069

 Never smoker

−0.303

−0.760, 0.155

0.195

−0.045

− 0.310, 0.219

0.737

− 0.009

−0.296, 0.277

0.949

−0.043

− 0.251, 0.166

0.688

CCI

0.392

−0.028, 0.812

0.067

−0.074

−0.294, 0.145

0.506

−0.046

− 0.289, 0.197

0.708

0.163

0.027, 0.299

0.019

Years diagnosed

−0.036

−0.073, 0.002

0.061

−0.034

− 0.052, − 0.015

< 0.001

−0.055

− 0.077, − 0.033

< 0.001

−0.027

− 0.040, − 0.013

< 0.001

 Active disease^a

–

–

–

–

–

–

–

–

–

–

–

–

 Remission

−0.982

−1.371, − 0.592

< 0.001

−1.120

−1.342, − 0.899

< 0.001

−1.031

− 1.272, − 0.79

< 0.001

−0.921

− 1.082, − 0.761

< 0.001

 Deep remission

−1.063

− 1.681, − 0.445

0.001

−1.513

− 1.837, − 1.189

< 0.001

−1.374

− 1.722, − 1.027

< 0.001

−1.110

− 1.348, − 0.872

< 0.001