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Table 3 Univariate and multivariate analysis of clinical factors associated with survival time after endoscopic biliary drainage

From: Effectiveness, safety, and factors associated with the clinical success of endoscopic biliary drainage for patients with hepatocellular carcinoma: a retrospective multicenter study

  

HR

Univariate

Multivariate

95% CI

p value

HR

95% CI

p value

Median age (years)

72

1

     
 

 > 72

0.83

0.53–1.30

0.42

   

Sex

Male

1

     
 

Female

0.87

0.52–1.42

0.59

   

History of radiation therapy

Present

1

     
 

Absent

1.02

0.62–1.76

0.95

   

Child–Pugh

A/B

1

  

1

  
 

C

1.7

1.04–2.71

0.035

1.17

0.64–2.13

0.62

Stage

I/II/III

1

  

1

  
 

IV

2.35

1.47–3.84

0.0005

1.53

0.82–2.84

0.18

BCLC classification

0/A/B

1

  

1

  
 

C/D

2.58

1.51–4.42

0.0002

1.02

0.40–2.59

0.97

Portal thrombosis

Present

1

  

1

  
 

Absent

0.44

0.27–0.70

0.0005

0.52

0.28–0.96

0.038

Biliary stricture

Present

1

     
 

Absent

0.68

0.30–1.33

0.28

   

Cholangitis

Present

1

     
 

Absent

0.82

0.53–1.30

0.41

   

Hemobilia

Present

1

     
 

Absent

1.48

0.92–2.44

0.11

   

Plastic stent

Single

1

     
 

Multiple

0.71

0.41–1.17

0.18

   

HCC treatment after ERCP

Absent

1

  

1

  
 

Present

0.32

0.18–0.52

 < 0.0001

0.39

0.21–0.70

0.0015

Clinical course

Success

1

  

1

  
 

Failure

3.2

1.87–5.37

 < 0.0001

2.59

1.42–4.71

0.0018