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Table 1 Background characteristics of the patient, overall and by CnLN examination status (N = 1178)

From: Central lymph node metastasis is predictive of survival in advanced gastric cancer patients treated with D2 lymphadenectomy

Variable

CnLN examined

P value

All patients (N = 1178)

Positive (N = 342)

Negative (N = 836)

Age, average, years

58.54 (7–84)

58.39 (23–81)

58.60 (7–81)

0.258

 < 60, N(%)

582 (49.4%)

169 (49.4%)

413 (49.4%)

0.997

 ≥ 60, N(%)

596 (50.6%)

173 (50.6%)

423 (50.6%)

Gender, N (%)

    

 Female

337 (28.6%)

98 (28.7%)

239 (28.6%)

0.517

 Male

841 (71.4%)

244 (71.3%)

597 (71.4%)

Diagnosed year

    

 2004–2006

185 (15.7%)

61 (17.8%)

124 (14.8%)

0.245

 2007–2009

359 (30.5%)

109 (31.9%)

250 (29.9%)

 2010–2012

634 (53.8%)

172 (50.3%)

462 (55.3%)

Tumor size

    

  ≤ 4 cm

480 (40.7%)

105 (30.7%)

375 (44.9%)

 < 0.001

 > 4 cm

698 (59.3%)

237 (69.3%)

461 (55.1%)

Number of examined LN, average

22.74 (3–119)

25.70 (4–119)

21.53 (3–82)

0.174

Number of positive LN, average

6.01 (1–118)

12.20 (1–118)

3.47 (3–79)

 < 0.001

Type of resection

    

 Total gastrectomy

202 (17.1%)

63 (18.4%)

139 (16.6%)

0.254

 Subtotal gastrectomy

976 (82.9%)

279 (81.6%)

697 (83.4%)

Location

    

 Antrum/pylorus

620 (52.6%)

183 (53.5%)

437 (52.3%)

0.428

 Body/fundus

124 (10.5%)

32 (9.4%)

92 (11.0%)

 GEJ/cardia

152 (12.9%)

38 (11.1%)

114 (13.6%)

 Total

282 (23.9%)

89 (26.0%)

193 (23.1%)

Histology grade

    

 Differentiated

441 (37.4%)

111 (32.5%)

330 (39.5%)

0.014

 Un-differentiated

737 (62.6%)

231 (67.5%)

506 (60.5%)

Signet ring cell

    

 Yes

119 (10.1%)

48 (14.0%)

71 (8.5%)

0.004

 No

1059 (89.9%)

294 (86.0%)

765 (91.5%)

Lymphatic vessel invasion

    

 Yes

280 (23.8%)

128 (37.4%)

152 (18.2%)

 < 0.001

 No

898 (76.2%)

214 (62.6%)

684 (81.8%)

Pathological T stage

    

 T2

220 (18.7%)

41 (12.0%)

179 (21.4%)

 < 0.001

 T3

666 (56.5%)

194 (56.7%)

472 (56.5%)

 T4

292 (24.8%)

107 (31.3%)

185 (22.1%)

Pathological N stage

    

 N0

323 (27.4%)

0 (0.0%)

323 (38.6%)

 < 0.001

 N1

219 (18.6%)

35 (10.2%)

184 (22.0%)

 N2

265 (22.5%)

84 (24.6%)

181 (21.7%)

 N3

371 (31.5%)

223 (65.2%)

148 (17.7%)