Table 3 Clinical Features of patients with Kawasaki Disease presenting with obstructive jaundice
Reference | Age | Hepato-megaly | Icterus | Abdominal Pain | Serum ALT(x ULN) | Serum AST(x ULN) | Serum ALP(x ULN) | Serum GGT(x ULN) | Serum Bilirubin(umol/L) | Pulmo-nary Involvement | Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
Our patient | 16 | + | + | + | 5.3 | 4.66 | 1.58 | 3.1 | 163 | + | IVIG 2 g/kg in divided doses of 0.8 g/kg on the first day and 1.2 g/kg on the second day. Oral Aspirin. Refractory Disease requiring a further 1 g/kg of IVIG over 2 days. |
Bader-Meunier et al. [17] | 3.5 | + | + | NR | 5 | 2.5 | 4 | 15 | 23.9 | – | IVIG 1 g/kg/day. Not refractory |
Keeling et al. [18] | 12 | + | + | + | 1.91 | 0.80 | 1.43 | 2.63 | 48.9 | – | IVIG 1.6 g/kg/day. Oral Aspirin. Not refractory |
McMahon et al. [19] | 20 | NR | + | + | 4.74 | 2.28 | 1.83 | 4.45 | 134.4 | – | IVIG 2 g/kg/day. Oral Aspirin. Not Refractory. |
Valentini et al. [20] | 6 | NR | + | + | 9.96 | 11.87 | 1 | 10.88 | 121.4 | – | IVIG 2 g/kg/day. Oral Aspirin. Not Refractory. |
Vázquez et al. [21] | 6 | + | + | NR | NR | NR | 3.21 | 4.02 | 98.3 | – | IVIG 2 g/kg/day. Refractory Disease requiring further IVIG 72 h after the 1st dose and 48 h of Methylprednisolone 15-30 mg/kg for 2 days. Oral Aspirin. |