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Fig. 2 | BMC Gastroenterology

Fig. 2

From: Role of sex hormones and their receptors on gastric Nrf2 and neuronal nitric oxide synthase function in an experimental hyperglycemia model

Fig. 2

Effect of sex hormone receptor antagonist (ER; ICI 182,780 and PR; RU-486) on NOSα, Nrf2, ER and BH4 synthesis enzyme mRNA expression. Gastric neuromuscular tissues incubated with sex hormone receptor antagonists for 48 h (a) nNOSα, (b) Nrf2, (c) GCH-1, (d) DHFR, (e&f) ERα, ERβ mRNA expression were measured via RT-qPCR. Data were normalized with housekeeping gene (β-actin). Bar graphs showed a ratio of target gene or protein with β-actin. Data were analyzed using one-way ANOVA by using GraphPad prism software. Data are means ± SEM (n = 4). * p < 0.05 compared with normal glycemia (NG) groups

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BMC Gastroenterology

ISSN: 1471-230X

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