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Table 3 Laboratory parameters at initiation of TG (T0) and 6 months of treatment (T6), shown as mean (SD). Levels of response and non-response group at T6 are compared, as are levels at T0 and T6 of the entire cohort

From: Efficacy, safety and drug survival of thioguanine as maintenance treatment for inflammatory bowel disease: a retrospective multi-centre study in the United Kingdom

Parameter

T0, Response

T6, Response

T0, Non-Response

T6, Non-Response

T0, Total

T6, Total

Haemoglobin

131 (14)

136 (17)*

128 (21)

132 (16)*

131 (16)

135 (18)*

Platelets

305 (87)

259 (95)*

332 (116)

309 (90)

313 (95)

275 (97)*

Bilirubin

8 (6)

9 (9)

7 (4)

8 (4)

8 (6)

9 (8)*

ALAT

24 (19)

25 (14)

20 (12)

20 (14)

23 (17)

24 (14)

AP

74 (30)

81 (38)

90 (31)

94 (58)

79 (32)

84 (41)

Albumin

44 (5)

44 (5)

44 (4)

44 (3)

44 (4)

44 (5)

CRP

12 (32)

9 (20)

9 (11)

26 (65)*

11 (29)

13 (36)

ESR

17 (20)

13 (12)

18 (15)

17 (14)

17 (16)

15 (12)

  1. ALAT Alanine aminotransferase, AP Alkaline phosphatase, CRP C-reactive protein, ESR Erythrocyte sedimentation rate
  2. *: statistical significantly different (P < 0.05)