Factors correlated with drug use for constipation: perspectives from the 2016 open Japanese National Database

Mihara, Hiroshi; Murayama, Aiko; Nanjo, Sohachi; Ando, Takayuki; Tajiri, Kazuto; Fujinami, Haruka; Yamada, Masaaki; Yasuda, Ichiro

doi:10.1186/s12876-020-01425-6

BMC Gastroenterology

Table 3 Relationships between variables and drugs to relieve constipation (N = 47 prefectures in Japan)

From: Factors correlated with drug use for constipation: perspectives from the 2016 open Japanese National Database

	Pearson correlation coefficients by type of drug used to relieve constipation
	Magnesium	Stimulant laxative	Fecal intervention	Suppositories and enemas
Aging (> 65 years)	0.583^**	0.693^**	0.552^**	0.303^*
Vasodilator claims/prescriptions (per 1000 people)	0.526^**	0.667^**	0.308^*	0.2
Female gender	0.434^**	0.562^**	0.592^**	0.453^**
Antihypertensive claims/prescriptions (per 1000 people)	0.389^**	0.794^**	0.338^*	0.1
Eating ≤2 h before bedtime	−0.366^*	− 0.288^*	− 0.372^**	− 0.1
Total crimes/10 month (per 1000 people)	− 0.334^*	− 0.515^**	− 0.386^**	− 0.2
Insomnia	− 0.327^*	− 0.2	− 0.326^*	− 0.1
Population density (per km²)	−0.308^*	− 0.348^*	− 0.405^**	− 0.2
Average humidity	0.293^*	0.353^*	0.310^*	0.2
Psychiatric specialty therapy (per 1000 people)	0.2	0.2	0.333^*	0.3
Antihypertensives	0.2	0.424^**	0.1	0.2
Daily alcohol intake	0.1	0.511^**	0.3	−0.1
Eating after dinner	0.1	0.2	0.291^*	0.344^*
Mean elevation above sea level	0.1	0.0	0.2	0.0
Eating rapidly	0.1	−0.2	0.1	0.317^*
Weight loss (BMI < 20 kg/m²)	0.0	−0.2	0.2	−0.2
30-min of vigorous exercise	0.0	−0.442^**	− 0.288^*	0.2
Average outside temperature	0.0	−0.622^**	−0.2	0.1
Hyperglycemia	0.0	0.2	0.1	0.2
Precipitation in capital city	−0.1	−0.1	0.0	−0.1
Waist circumference > 90 cm	−0.1	− 0.1	−0.2	0.1
Obese (BMI > 25 kg/m²)	−0.1	0.1	−0.2	0.1
Total worker household income	−0.2	−0.2	− 0.299^*	−0.355^*
Walking > 1 h	− 0.2	− 0.1	− 0.1	− 0.1
Average room temperature	−0.2	0.364^*	0.1	−0.1
Total household income	−0.2	− 0.2	− 0.3	−0.353^*
Smoking	−0.2	0.489^**	0.0	− 0.3
Female average income	−0.2	− 0.522^**	− 0.343^*	−0.2
No breakfast	−0.2	− 0.334^*	− 0.2	0.0
Walking fast	−0.2	−0.2	− 0.2	0.1
Male average income	−0.3	− 0.513^**	−0.380^**	− 0.3

BMI body mass index
*p < 0.05, **p < 0.01

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