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Table 2 β-Catenin nuclear and cytoplasmic expression tabulated as intensity and percentage in normal, advanced adenoma, and CRC

From: Analysis of β-catenin association with obesity in African Americans with premalignant and malignant colorectal lesions

 

Normal

N = 32

Advanced Adenoma N = 74

CRC

N = 46

Overall P value

P value for Advanced Adenoma vs. Normal

P value for CRC vs. other

C%

100 (10–100)

100 (80–100)

100 (100–100)

0.004

0.3

0.07

N%

0 (0–0)

0 (0–0)

0 (0–10)

0.009

0.006

0.012

C Intensity +

26 (81%)

74 (100%)

46 (100%)

< 0.001

< 0.001

0.1

N Intensity +

0

18 (24%)

19 (41%)

< 0.001

0.002

0.001

  1. C Cytoplasmic, N Nuclear
  2. C Intensity+ and N Intensity+ mean Intensity 1 and above