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Table 1 Characteristics of patients with suspected infectious diarrhea evaluated before and after introduction of FilmArray GI PCR

From: Use of BioFire FilmArray gastrointestinal PCR panel associated with reductions in antibiotic use, time to optimal antibiotics, and length of stay

Characteristic

Overall

FilmArray group

Pre-FilmArray group

P-value*

Total

 N

170

129

41

Sex

 Male – N (%)

79 (46.5%)

65 (50.4%)

14 (34.1%)

0.0120

Age

 Years – mean ± std. dev.

47.4 ± 18.4

45.6 ± 18.4

56.7 ± 17.9

0.0011

Prior history of CDI

 Prior C. difficile documented in chart – N (%)

22 (12.9%)

13 (10.1%)

9 (22.0%)

< 0.0001

CDI diagnosis (by ICD-9/ICD-10 code)

Clostridium difficile enteritis/colitis – N (%)

102 (60.0%)

68 (52.7%)

34 (82.9%)

< 0.0001

Time to overall disposition from ED

 Hours – median [Q1,Q3]

7 [5,10]

7 [5.5,10]

7 [4,10.5]

0.6052

Time to discharge from ED

 Hours – median [Q1,Q3]

7 [5,10]

7.5 [5,10]

7 [6,15]

0.5618

Time to admission to hospital

 Hours – median [Q1,Q3]

7 [5,10]

7 [6,10]

7 [4,10]

0.4542

Hospital admission

 Admitted from ED to hospital – N (%)

117 (68.8%)

81 (62.8%)

36 (87.8%)

< 0.0001

Hospital length of stay (LOS)

 Days – median [Q1,Q3]

4 [2,8]

3 [2,6]

7.5 [4,10]

0.0002

Day on which empiric antibiotics started

 Days – median [Q1,Q3]

1 [1,1]

1 [1,1]

1 [1,1]

0.3298

Day on which optimal antibiotics started

 Days – median [Q1,Q3]

2 [1,2]

1 [1,2]

2 [1,3]

0.0117

Optimal antibiotics prescribed on first try

 Discharged with initial antibiotics – N (%)

70 (41.2%)

61 (47.3%)

9 (22.0%)

< 0.0001

Discharged without antibiotics

 Antibiotics not prescribed or discontinued – N (%)

20 (11.8%)

18 (14.0%)

2 (4.9%)

< 0.0001

  1. * Welch’s t-test or Wilcoxon ranked-sum test (Mann-Whitney U-test) for continuous variables, Chi-squared test for categorical variables