Clinical and genomic characteristics of mucosal signet-ring cell carcinoma in Helicobacter pylori-uninfected stomach

Table 1 Comparison of Helicobacter pylori-uninfected and -infected mucosal signet ring cell carcinoma

	HpU-SRCC (n = 17)	HpI-SRCC (n = 34)	p-value
male/female	15/2	14/20	0.004
age	53.2 ± 11.4	58.2 ± 13.2	n.s.
location
upper third	2 (11.8%)	0	n.s.
middle third	4 (23.5%)	24 (70.6%)
lower third	11 (64.7%)	10 (29.4%)
size	9.1 ± 5.3	16.0 ± 11.7	0.03
blood type (A/B/O/AB)	8/1/5/3	16/4/9/5	n.s.
family history^a of gastric cancer	6/13 (46%)	7/23 (30%)	n.s.
alcohol	10/17 (59%)	16/26 (62%)	n.s.
smoking	11/17 (65%)	6/26 (23%)	0.02
Brinkman Index	563.6	526.7

HpU-SRCC: Helicobacter pylori (H. pylori)-uninfected signet-ring cell carcinoma, HpI-SRCC: H. pylori-infected signet-ring cell carcinoma, n.s.: not significant
^a Family History: relative within the 3-degree relationship
With drinking history, drink alcohol 21.6 g/day or more and drink more than 3 days a week as a drinker. And with smoking history, defined including smoking in present and in the past

ISSN: 1471-230X