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Table 1 Diagnosis of idiopathic hypereosinophilic syndrome (HES)

From: Colon perforation due to cytomegalovirus infection in a patient with idiopathic hypereosinophilic syndrome: a case report

Exclusion of the following diseases

1. Reactive eosinophilia

2. Lymphocyte-variant hypereosinophilia (cytokine-producing, immunophenotypically-aberrant T-cell population)

3. Chronic eosinophilic leukemia, NOS

4. WHO-defined myeloid malignancies associated eosinophilia (e.g. MDS, MPNs, MDS/MPNs, or AML)

5. Eosinophilia-associated MPNs or AML/ALL with rearrangements of PDGFRA, PDGFRB, or FGR1.

  1. Abbreviations: NOS not other specified, MDS myelodysplastic syndrome, MPNs myeloproliferative neoplasms, AML acute myeloid leukemia, ALL acute lymphoblastic leukemia, PDGFRA platelet-derived growth factor receptor alpha, PDGFRB platelet-derived growth factor receptor beta, FGR1 fibroblast growth factor receptor 1
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BMC Gastroenterology

ISSN: 1471-230X

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