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Table 1 Summary of outcomes of rifabutin based triple therapy in H. pylori infection

From: Rescue therapy with rifabutin regimen for refractory Helicobacter pylori infection with dual drug-resistant strains

Author(s) and year Country Drugs and doses Duration of treatment (days) No. of patients No. of previously failed treatment Eradication rate (%)
Fiorini G 2018 [18] Italy. esomeprazole 40 mg bid, amoxicillin 1 g bid, and rifabutin 150 mg od 12 254 2 82.9% intention-to-treat
Ribaldone DG 2019 [19] Italy. Rifabutin 150 mg bid
Amoxicillin 1 g bid
PPI bid
14 302 2 71.5% intention-to-treat
Van Zanten et al. 2010 [16] Canada Rifabutin 300 mg od
Amoxicillin 1 g bid
PPI bid
7 16 3 63%
Lim et al. 2014 [17] Korea Rifabutin 150 mg bid
Amoxicillin 1 g tid
Lansoprazole 60 mg bid
7 27 2 96.3 intention-to-treat
Lim et al. 2014 [17] Korea Rifabutin 150 mg bid
Amoxicillin 1 g tid
Lansoprazole 30 mg bid
7 32 2 78.1 intention-to-treat
Ierardi et al. 2014 [20] Italy Rifabutin 150 mg bid
Minocycline 100 mg bid
Bismuth 120 mg qid
Rabeprazole 20 mg bid
10 21 2 77.7%