Table 1 Summary of outcomes of rifabutin based triple therapy in H. pylori infection
Author(s) and year | Country | Drugs and doses | Duration of treatment (days) | No. of patients | No. of previously failed treatment | Eradication rate (%) |
|---|---|---|---|---|---|---|
Fiorini G 2018 [18] | Italy. | esomeprazole 40 mg bid, amoxicillin 1 g bid, and rifabutin 150 mg od | 12 | 254 | 2 | 82.9% intention-to-treat |
Ribaldone DG 2019 [19] | Italy. | Rifabutin 150 mg bid Amoxicillin 1 g bid PPI bid | 14 | 302 | 2 | 71.5% intention-to-treat |
Van Zanten et al. 2010 [16] | Canada | Rifabutin 300 mg od Amoxicillin 1 g bid PPI bid | 7 | 16 | 3 | 63% |
Lim et al. 2014 [17] | Korea | Rifabutin 150 mg bid Amoxicillin 1 g tid Lansoprazole 60 mg bid | 7 | 27 | 2 | 96.3 intention-to-treat |
Lim et al. 2014 [17] | Korea | Rifabutin 150 mg bid Amoxicillin 1 g tid Lansoprazole 30 mg bid | 7 | 32 | 2 | 78.1 intention-to-treat |
Ierardi et al. 2014 [20] | Italy | Rifabutin 150 mg bid Minocycline 100 mg bid Bismuth 120 mg qid Rabeprazole 20 mg bid | 10 | 21 | 2 | 77.7% |