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Table 2 Summary of published case reports of generalized CSH treated in the era of novel agents

From: A colonic mass revealing a disseminated crystal storing histiocytosis secondary to indolent multiple myeloma: a case report with literature review

Reference date of publication Age Sex Underlying disease Organ involvment Evolution before diagnosis Ig Treatment Haematological response Organ response Evolution
Boudhabhay [7] 2018 60 M multiple myeloma cornea, kidney 2 years IgGkappa bortezomib-lenalidomide-dexamethasone PR NO End stage renal failure
Wu [8] 2017 48 M multiple myeloma kidney Unknown IgGkappa bortezomib-cyclophosphamide-dexamethasone VGPR NO End stage renal failure
Aline-Fardin[9] 2015 69 M monoclonal gammopathy mesenteric panniculitis, lympho node, kidney 6 months LC kappa bortezomib-DXM VGPR YES Persistent remission (12 months)
Baird [10] 2015 53 F lymphoplasmocytic lymphoma lung, mediastinal lymph node, bone marrow 18 months IgM lambda bortezomib-cyclophosphamide-dexamethasone-rituximab VGPR YES Remission
Hu [11] 2012 48 F multiple myeloma spleen, bone marrow 2 years IgGkappa bortezomib-thalidomide-dexamethasone-rituximab VGPR YES Remission
Robak [12] 2002 54 M lymphoplasmocytic lymphoma spleen, bone marrow 1 year IgAkappa ritixmab PR NO Pancytopenia
  1. F Female; M Male; PR Partial response; VGPR Very good partial response