Table 2 Comparison of composite NAFLD Activity Score (NAS) in human NASH patients and GAN DIO-NASH mice
From: Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis
NAS | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Group | n | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
Human subjects | Healthy normal-weight | 14 | 13 | 1 | – | – | – | – | – | – | – |
NASH | 16 | – | – | – | – | – | 12 | 4 | – | – | |
C57BL/6 J mice | Chow-fed lean mice | 10 | 10 | – | – | – | – | – | – | – | – |
GAN DIO-NASH mice | 25 | – | – | – | – | 6 | 7 | 11 | 1 | – | |