Evaluation of breath, plasma, and urinary markers of lactose malabsorption to diagnose lactase non-persistence following lactose or milk ingestion

Table 2 Participant demographics

Measure^a	LP genotypes^b		LNP genotypes	p value^c
Measure^a	LP Homozygote (n = 16) TT₁₃₉₁₀ / AA₂₂₀₁₈	LP Heterozygote (n = 10) CT₁₃₉₁₀ / GA₂₂₀₁₈	LNP Homozygote (n = 14) CC₁₃₉₁₀ / GG₂₂₀₁₈	p value^c
BMI (kg/m²)	22.5 ± 0.5	22.3 ± 0.5	24.4 ± 1.0	0.098
Age (years)	26.8 ± 0.6	24.2 ± 0.96	26.2 ± 0.68	0.060
Glucose (mmol/L)	5.52 ± 0.20	5.15 ± 0.16	5.5 ± 0.21	0.758
Triglycerides (mmol/L)	1.12 ± 0.11	1.11 ± 0.09	1.09 ± 0.09	0.965
Insulin (μU/mL)	13.39 ± 3.44	9.94 ± 1.5	13.64 ± 3.01	0.687

^a Glucose, triglycerides and insulin measures in plasma
^b Values presented as mean ± SEM. Genotypes for lactase persistence classification taken from [12, 48]
^cp value was computed using linear mixed model
BMI body mass index, LNP lactase non-persistence, LP lactase persistence

ISSN: 1471-230X