Fig. 4

Stability of fecal microbiota composition the first year after ileocaecal resection. Fecal microbiota from 8 CD patients at early follow up (3–10 weeks after ileocaecal resection) and at the 1-year follow, and from 13 patients at the 1 year follow up was analyzed by the GA-map™ Dysbiosis test. a PCA based on fecal microbiota composition (X-variables; n = 54) from 8 CD patients at early follow up and from the same patients at the 1-year follow up. Lines to the centroid, showing the group mean, connect each group. Individual patients are marked from a-h for each time point. b PCA displaying the within-patient mobility of fecal microbial composition from early follow up to 1-year follow up in relation to the total population at the 1-year follow up (n = 21) (paired samples indicated with arrows pointing from early to 1-year follow up, n = 8). c Within-patient microbial similarity from early follow up to 1-year follow up (top, n = 8) in relation to between-patient similarity from early follow up to 1-year follow up (middle, n = 8), and to between-patient similarity at 1 year follow up (bottom, n = 21) analyzed by Bray-Curtis dissimilarity index. Between-patient dissimilarities show mean values for a unique individual to all non-related patients (mean of n = 20). Closed and open circles represent patients with disease relapse and remission, respectively, at the 1-year postsurgical follow-up; *** p ≤ 0.001