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Table 4 Comparison of patients with HBsAg loss at EOT and in Group 1

From: HBsAg quantification predicts off-treatment response to interferon in chronic hepatitis B patients: a retrospective study of 250 cases

Variables

EOT HBsAg loss group

HBsAg loss in Group 1

p-value

Gender, male (%)

5 (83.3%)

12 (70.6%)

0.541

Age (years)

24.8 ± 2.7

26.5 ± 5.7

0.496

Baseline ALT (U/L)

249.8 ± 214.0

133.6 ± 130.1

0.127

Baseline HBV DNA (log10IU/mL)

4.3 ± 1.5

5.8 ± 2.1

0.133

Baseline HBsAg (log10IU/mL)

2.6 ± 0.9

2.9 ± 0.6

0.399

On-treatment HBsAg decline at week 24 (log10IU/mL)

1.6 ± 1.4

1.2 ± 0.8

0.37

On-treatment HBV DNA decline at week 24 (log10IU/mL)

1.9 ± 1.6

3.7 ± 1.6

0.041

Duration of IFN (months)

17.3 ± 4.9

14.5 ± 5.2

0.254

  1. P-value < 0.05 is shown in bold italics