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Table 3 Logistic regression analysis of preoperative factors predicting LNM based on pathology in patients with LAGC

From: The significance of preoperative serum carcinoembryonic antigen levels in the prediction of lymph node metastasis and prognosis in locally advanced gastric cancer: a retrospective analysis

Variables

 

Univariate analysis

Multivariate analysis

LNM -, n (%)

LNM +, n (%)

p value

OR

95%CI

p value

Gender

Male

66(71.7)

137(74.5)

0.665

   

female

26(28.3)

47(25.5)

    

Age (years)

≤60

50(54.3)

113(61.4)

0.299

   

> 60

42(45.7)

71(38.6)

    

Tumor location

Upper

16(17.4)

46(25)

0.146

   

Middle

50(54.3)

78(42.4)

    

lower

26(28.3)

60(32.6)

    

CA199 (U/ml)

≤37

87(94.6)

147(79.9)

0.001

1

  

> 37

5(5.4)

37(20.1)

 

2.265

0.672–7.632

0.187

CA125 (U/ml)

≤35

90(97.8)

172(93.5)

0.152

   

> 35

2(2.2)

12(6.5)

    

CEA (ng/ml)

≤3.4

76(82.6)

87(47.3)

<  0.001

1

 

< 0.001

> 3.4

16(17.4)

97(52.7)

 

4.86

2.33–10.139

 

LNM base on CT or MRI

No

88(95.7)

57(31)

< 0.001

1

 

< 0.001

Yes

4(4.3)

127(69)

 

47.81

16.34–139.9

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