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Fig. 2 | BMC Gastroenterology

Fig. 2

From: 25(OH) D3 alleviate liver NK cytotoxicity in acute but not in chronic fibrosis model of BALB/c mice due to modulations in vitamin D receptor

Fig. 2

Chronic CCl4 mice model was associated with decreased pHSCs VDR and hypercalcemia. a. High Ca+ 2 serum levels were obtained following vitamin D treatments only on the chronic model (p < 0.05). b. A significant drop in serum vitamin D levels were seen in acute mice model of CCl4 following vitamin D treatments while no changes were seen in the chronic model. c. Inhibition of VDR in pHSCs in the chronic model of CCl4 while up-regulation of the VDR were obtained in acute model by western blot

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