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Table 2 Ability to predict mucosal inflammation (MES 2 or 3) with optimal cutoff value by ROC curve

From: Serum amyloid A is a better predictive biomarker of mucosal healing than C-reactive protein in ulcerative colitis in clinical remission

 

CRP

SAA

Sensitivity (95% CI)

0.620 (0.504–0.727)

0.722 (0.609–0.817)

Specificity (95% CI)

0.758 (0.672–0.832)

0.850 (0.773–0.909)

PPV (95% CI)

0.628 (0.511–0.735)

0.760 (0.647–0.851)

NPV (95% CI)

0.752 (0.665–0.826)

0.823 (0.744–0.885)

Accuracy (95% CI)

0.704 (0.635–0.766)

0.799 (0.737–0.852)

  1. CI Confidence interval, CRP C-reactive protein, MES Mayo Endoscopic Score, NPV Negative predictive interval, PPV Positive predictive value, SAA Serum amyloid A