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Table 4 Toxicity and clinical characteristics

From: Correlation between UGT1A1 gene polymorphism and irinotecan chemotherapy in metastatic colorectal cancer: a study from Guangxi Zhuang

Clinical feature

Diarrhea

P

Neutropenia

P

0 grade

1–2 grade

3–4 grade

0 grade

1–2 grade

3–4 grade

Age (years)

  < 60

31

12

6

0.332

28

11

10

0.235

  ≥ 60

21

7

9

15

14

8

Gender

 Male

32

12

10

0.936

27

15

12

0.905

 Female

20

7

5

16

10

6

PS score

 0

17

7

5

0.947

13

9

7

0.776

 1

35

12

10

30

16

11

Tumor site

 Colon

23

8

5

0.753

18

11

7

0.945

 Rectum

29

11

10

25

14

11

N of metastatic organs

 1

31

12

8

0.843

25

15

11

0.974

 2

21

7

7

18

10

7