From: Helicobacter pylori infection as a risk factor for diabetes: a meta-analysis of case-control studies
Subgroup | Number of studies | Summery Odds Ratio (95% CI) | Between studies | Between subgroups | |||
---|---|---|---|---|---|---|---|
I2 | Pheterogeneity | Q | Q | Pheterogeneity | |||
Type of diabetes | |||||||
 Diabetes Mellitus | 11 | 1.17 (0.94–1.45) | 82.5% | 0.0001 | 1.43 |  |  |
 Type 1 Diabetes | 15 | 1.19 (0.98–1.45) | 81.6% | 0.0001 | 1.75 | 3.59 | 0.0001 |
 Type 2 Diabetes | 15 | 1.43 (1.11–1.85) | 90.0% | 0.0001 | 2.72 |  |  |
Continent | |||||||
 Asian | 12 | 1.41 (1.05–1.88) | 93.2% | 0.0001 | 2.29 |  |  |
 American | 2 | 0.45 (0.31–0.66) | 0.0% | 0.728 | 4.12 | 3.59 | 0.001 |
 African | 7 | 1.32 (1.05–1.66) | 61.0% | 0.018 | 2.40 |  |  |
 European | 20 | 1.26 (1.08–1.47) | 80.3% | 0.0001 | 2.94 |  |  |
Mean of HbA1Ca | |||||||
 6–8 | 9 | 1.40 (0.92–2.13) | 95.0% | 0.001 | 1.55 |  |  |
 8 < | 13 | 1.41 (1.20–1.64) | 73.7% | 0.001 | 4.33 | 3.59 | 0.0001 |
Duration of Diabetesa | |||||||
 0–3 Y | 7 | 1.18 (1.06–1.31) | 0.0% | 0.450 | 3.07 |  |  |
 4–7 Y | 10 | 1.15 (0.95–1.38) | 69.1% | 0.001 | 1.45 | 3.59 | 0.001 |
 8 < Y | 9 | 1.09 (0.79–1.51) | 91.0% | 0.0001 | 0.55 |  |  |
Method of detection bacteria | |||||||
 Invasive Tests | 18 | 1.07 (0.93–1.23) | 73.2% | 0.0001 | 1.00 |  |  |
 Non- Invasive Test | 23 | 1.45 (1.19–1.76) | 88.5% | 0.0001 | 3.70 | 3.59 | 0.0001 |
Agea | |||||||
 10–30 Y | 15 | 1.30 (1.05–1.62) | 81.9% | 0.0001 | 2.37 |  |  |
 30–60 Y | 18 | 1.34 (1.09–1.65) | 91.3% | 0.0001 | 2.77 | 3.59 | 0.0001 |
 60 < Y | 3 | 1.03 (0.68–1.57) | 76.4% | 0.014 | 0.15 |  |  |
NOS Score | |||||||
 6 | 11 | 1.14 (0.85–1.53) | 87.7% | 0.0001 | 0.86 |  |  |
 7 | 16 | 1.42 (1.10–1.82) | 89.0% | 0.0001 | 2.72 |  |  |
 8 | 12 | 1.24 (1.00–1.53) | 81.6% | 0.0001 | 1.96 | 3.59 | 0.0001 |
 9 | 2 | 1.08 (0.95–1.22) | 35.0% | 0.216 | 1.14 |  |  |