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Table 4 Sustained Virologic Response Rates (95% Confidence Intervals) in Patients infected with HCV Genotype 2, 4, and 6

From: Real-world effectiveness and safety of sofosbuvir and nonstructural protein 5A inhibitors for chronic hepatitis C genotype 1, 2, 3, 4, or 6: a multicentre cohort study

 

Genotype 2 SVR, % (95% CI)

Genotype 4 SVR, % (95% CI)

Genotype 6 SVR, % (95% CI)

All patients

DAC + SOF

SOF/VEL

All patients

LDV/SOF

DAC + SOF

All patients

LDV/SOF

DAC + SOF

SOF/VEL

Patients who complete, N

14

10

4

11

1

10

152

36

109

7

 All durations

100 (78.5–100)

100 (72.2–100)

100 (51.0–100)

90.9 (62.3–98.4)

100 (20.7–100)

90.0 (59.6–98.2)

96.7 (92.5–98.6)

97.2 (85.8–99.5)

96.3 (90.9–98.6)

100 (64.6–100)

 12-wk treatment

100 (77.2–100)

100 (70.1–100)

100 (51.0–100)

87.5 (52.9–97.8)

100 (20.7–100)

85.7 (48.7–97.4)

97.1 (92.9–98.9)

97.0 (84.7–99.5)

97.0 (91.5–99.0)

100 (64.6–100)

 16-wk treatment

NA

NA

NA

NA

NA

NA

100 (34.2–100)

NA

100 (34.2–100)

NA

 24-wk treatment

100 (20.7–100)

100 (20.7–100)

NA

100 (43.9–100)

NA

100 (43.9–100)

90.0 (59.6–98.2)

100 (43.9–100)

85.7 (48.7–97.4)

NA

SVR in the following subgroups

 No cirrhosis

100 (74.1–100)

100 (64.6–100)

100 (51.0–100)

100 (61.0–100)

100 (20.7–100)

100 (56.6–100)

96.8 (90.9–98.9)

100 (82.4–100)

95.8 (88.5–98.6)

100 (43.9–100)

 Cirrhosis

100 (43.9–100)

100 (43.9–100)

NA

80.0 (37.6–96.4)

NA

80.0 (37.6–96.4)

96.6 (88.5–99.1)

94.4 (74.2–99.0)

97.3 (86.2–99.5)

100 (51.0–100)

 Decompensated cirrhosis

100 (20.7–100)

100 (20.7–100)

NA

100 (20.7–100)

NA

100 (20.7–100)

100 (67.6–100)

100 (34.2–100)

100 (56.6–100)

100 (20.7–100)

 Treatment-naive

100 (75.8–100)

100 (67.6–100)

100 (51.0–100)

83.3 (43.6–97.0)

NA

83.3 (43.6–97.0)

99.1 (94.8–99.8)

100 (88.6–100)

98.6 (92.3–99.7)

100 (61.0–100)

 Treatment-experienced

100 (34.2–100)

100 (34.2–100)

NA

100 (56.6–100)

100 (20.7–100)

100 (51.0–100)

91.3 (79.7–96.6)

83.3 (43.6–97.0)

92.3 (79.7–97.3)

100 (20.7–100)