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Table 6 Univariate and multivariate analysis of risk factors for bleeding during and after colorectal endoscopic mucosal resection (EMR)

From: Colorectal endoscopic mucosal resection with submucosal injection of epinephrine versus hypertonic saline in patients taking antithrombotic agents: propensity-score-matching analysis

 

Risk factor for immediate EMR bleeding

Risk factor for post EMR bleeding

Variables

Odds ratio

95% CI

P value

Odds ratio

95% CI

P value

Univariate analysis

 Age, >75 y

0.48

0.09

2.48

0.48

2.38

0.64

8.79

0.20

 Sex, male

3.05

0.39

13.5

0.15

0.51

0.06

4.16

1.00

 Anticoagulant agents

1.07

0.20

5.56

1.00

2.27

0.61

8.53

0.25

 Antiplatelet agents

0.77

0.15

3.99

0.67

0.58

0.14

2.39

0.43

 Multiple agents

0.84

0.10

7.20

1.00

1.54

0.30

7.73

0.64

 Heparin replacement

1.07

0.21

5.56

1.00

0.79

0.16

3.90

1.00

 Size of polyps, >10 mm

5.57

1.27

24.5

0.024

2.11

0.56

7.90

0.27

 Number of polyps, > 2

0.23

0.03

1.93

0.26

2.74

0.74

10.2

0.17

 Histological classification, 0-Ip

3.81

0.74

19.4

0.14

1.21

0.34

4.34

1.00

 Operator of trainees

4.69

0.56

39.1

0.15

0.95

0.26

3.49

1.00

 Injection of epinephrine

3.16

0.62

16.2

0.28

2.46

0.61

9.88

0.33

Multivariate analysis

 Size of polyps, >10 mm

12.1

2.00

74.0

0.001

    
  1. 95% CI: 95% confidence interval