Indirect costs associated with ulcerative colitis: a systematic literature review of real-world data

BMC Gastroenterology

Table 3 Indirect costs associated with absenteeism, specifically sick leave in UC

Author, year	Country	Patients’ type	% of patients experiencing sick leave	Number of sick leaves days per patient per year	Cost			Cost adjusted
Author, year	Country	Patients’ type	% of patients experiencing sick leave	Number of sick leaves days per patient per year	Average cost (€) of sick leave per patient per year	Total average productivity loss in Euros per year	Currency, base year	Average cost (€) of sick leave per patient per year	Total average productivity loss in Euros per year	Currency, base year
Mandel et al. 2014 [1]	Hungary	Pooled UC patients	NR	10.14^a	485	1795	EURO, 2013	506	1872	$, 2017
Malinowski et al. 2016 [16]	Poland	Pooled UC patients	NR	13.49	787^e	1260^e	EURO, 2012	823	1318	$, 2017
Aldeguer et al. 2016 [17]	Spain	Pooled UC patients	22%	26.17	311	399	EURO, 2012	326	418	$, 2017
Van der Valk et al. 2012 [23]	The Netherlands	Pooled UC patients	NR	NR	1912^d	NR	EURO, 2010	2401.6	NR	$, 2017
Van der Valk et al. 2014 [19]	The Netherlands	Pooled UC patients	13.4%^b	10^cg	1447 ^kg	1580^g	EURO, 2011	1608.4	1756	$, 2017
Van der Valk et al. 2015 [29]	The Netherlands	Pouch patients	10.50%	8^h	1932^h	NR	EURO, 2011	2147.5	NR	$, 2017
Van der Valk et al. 2015 [29]	The Netherlands	Ileostomy patients	13.50%	20ⁱ	1508ⁱ	NR	EURO, 2011	1676.2	NR	$, 2017
Van der Valk et al. 2015 [29]	The Netherlands	Anti-TNF patients	23.90%	28^j	4340^j	NR	EURO, 2011	4824.1	NR	$, 2017
Kawalec et al. 2017 [14]	Poland	Pooled UC patients	NR	30.49	679	2043	EURO, 2014	710.6	2138	$, 2017
Hellström et al. 2017 [26]	Sweden	Pooled UC patients	NR	63^f	5309^f	NR	EURO, 2014	5391	NR	$, 2017

^aMissed working hours: The study reports missed working hours of 1.56 h per week equivalent of 10.14 days per year
^bUnpaid work: 28; 3.0%
^cUnpaid work: 7.8 days per 3 months
^dThe study reports 478€ per 3 month
^eGross domestic product per capita
^fThe study reports 50,925 SEK per year equivalent to either 5338 euros or 6297€ and it has been reported in the study it was reported as 9 weeks per year
^gThe study reports 2.5 days per 3 months and 361.79€ per 3 month
^hThe study reports 2 days per 3 months and 483€ per 3 month
ⁱThe study reports 5 days per 3 months and 377€ per 3 month
^jThe study reports 7 days per 3 months and 1085€ per 3 month
^kUnpaid work: 18.33€ per 3 months

ISSN: 1471-230X