Table 1 Demographics and Clinical Characteristics of Patients with Colorectal Cancer in the Study
Variable | All Patients (N = 384,996) | Tumor Histology | P value | ||
|---|---|---|---|---|---|
AC (N = 349,891) | MAC (N = 30,965) | SRCC (N = 4140) | |||
Sex, No. (%) | < .001 | ||||
Male | 201,826 (52.4) | 184,408 (52.7) | 15,221 (49.2) | 2197 (53.1) | |
Female | 183,170 (47.6) | 165,483 (47.3) | 15,744 (50.8) | 1943 (46.9) | |
Age, y, No. (%) | < .001 | ||||
≤ 44 y | 19,932 (5.2) | 17,632 (5.0) | 1819 (5.9) | 481 (11.6) | |
45-59y | 91,886 (23.9) | 84,785 (24.2) | 6151 (19.9) | 950 (22.9) | |
60-74y | 141,249 (36.7) | 129,226 (36.9) | 10,646 (34.4) | 1377 (33.3) | |
≥ 75y | 131,929 (34.3) | 118,248 (33.8) | 12,349 (39.9) | 1332 (32.2) | |
Marital status, No. (%) | < .001 | ||||
Unmarried | 205,102 (53.3) | 186,964 (53.4) | 15,941 (51.5) | 2197 (53.1) | |
Married | 160,284 (41.6) | 144,728 (41.4) | 13,778 (44.5) | 1778 (42.9) | |
Unknown | 19,610 (5.1) | 18,199 (5.2) | 1246 (4.0) | 165 (4.0) | |
T, No. (%) | < .001 | ||||
T0 | 567 (0.1) | 499 (0.1) | 60 (0.2) | 8 (0.2) | |
Tis | 14,784 (3.8) | 14,650 (4.2) | 108 (0.3) | 26 (0.6) | |
T1 | 67,426 (17.5) | 65,451 (18.7) | 1692 (5.5) | 283 (6.8) | |
T2 | 50,455 (13.1) | 46,734 (13.4) | 3550 (11.5) | 171 (4.1) | |
T3 | 180,679 (46.9) | 161,305 (46.1) | 17,606 (56.9) | 1768 (42.7) | |
T4 | 52,617 (13.7) | 44,210 (12.6) | 6884 (22.2) | 1523 (36.8) | |
Tx | 18,468 (4.8) | 17,042 (4.9) | 1065 (3.4) | 361 (8.7) | |
N, No. (%) | < .001 | ||||
N0 | 230,313 (59.8) | 212,807 (60.8) | 16,251 (52.5) | 1255 (30.3) | |
N1 | 89,719 (23.3) | 80,920 (23.1) | 7874 (25.4) | 925 (22.3) | |
N2 | 53,294 (13.8) | 45,509 (13.0) | 6087 (19.7) | 1698 (41.0) | |
NX | 11,670 (3.0) | 10,655 (3.0) | 753 (2.4) | 262 (6.3) | |
M, No. (%) | < .001 | ||||
M0 | 310,099 (80.5) | 282,887 (80.9) | 24,669 (79.7) | 2543 (61.4) | |
M1 | 74,512 (19.4) | 66,626 (19.0) | 6291 (20.3) | 1595 (38.5) | |
MX | 385 (0.1) | 378 (0.1) | 5 (0.0) | 2 (0.0) | |
Stage, No. (%) | < .001 | ||||
0 | 14,784 (3.8) | 14,650 (4.2) | 108 (0.3) | 26 (0.6) | |
I | 95,327 (24.8) | 91,062 (26.0) | 4007 (12.9) | 258 (6.2) | |
II | 98,990 (25.7) | 87,722 (25.1) | 10,643 (34.4) | 625 (15.1) | |
III | 101,383 (26.3) | 89,831 (25.7) | 9916 (32.0) | 1636 (39.5) | |
IV | 74,512 (19.4) | 66,626 (19.0) | 6291 (20.3) | 1595 (38.5) | |
Grade, No. (%) | < .001 | ||||
I | 32,258 (8.4) | 29,373 (8.4) | 2861 (9.2) | 24 (0.6) | |
II | 244,735 (63.6) | 226,222 (64.7) | 18,318 (59.2) | 195 (4.7) | |
III | 58,637 (15.2) | 50,223 (14.4) | 5603 (18.1) | 2811 (67.9) | |
IV | 7371 (1.9) | 6053 (1.7) | 853 (2.8) | 465 (11.2) | |
Unknown | 41,995 (10.9) | 38,020 (10.9) | 3330 (10.8) | 645 (15.6) | |