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Table 1 Comparison between the screened and the final study cohort

From: Association between serum IgG level and clinical course in primary sclerosing cholangitis

 

Final study cohort N = 148

Screened cohort N = 446

p-value

Gender [Male %f]

105 (70.9%)

312 (70.0%)

P = 0.82

Median age at initial diagnose [in years]

33.5 (26–47)

32 (24–44)

P = 0.21

Median time of follow-up [in years]

9 (3–14)

9 (4–14)

P = 0.91

Patients diagnosed with AIH/PSC overlap

9 (6.1%)

29 (6.6%)

P = 0.82

Presence of dominant stenosis

87 (58.8%)

268 (60.6%)

P = 0.72

Presence of IBD

99 (66.9%)

315 (70.9%)

P = 0.42

BMI

22.7 (17.1–31.9)

22.7 (17.3–56.7)

P = 0.5

Mayo Risk Score (MRS)

−0.2 (−3.1–2.3)

−0.1 (− 2.7–2.8)

P = 0.8

OLT

32 (21.6%)

107 (30.4%)

P = 0.042

Re-OLT

9 (6.1%)

21 (6%)

P = 1.02

Death

37 (25%)

66 (18.8%)

P = 0.22

Combined end-point (OLT and death)

57 (38.5%)

144 (40.9%)

P = 0.62

CCA

12 (8.1%)

31 (8.8%)

P = 0.82

  1. 1Mann-Witney- U test was applied
  2. 2Chi2-Test was applied
  3. Abbreviation: AIH/PSC = autoimmune hepatitis/primary sclerosing cholangitis, CCA = cholangiocarcinoma, IBD = Inflammatory bowel disease, MRS = Mayo Risk ScoreOLT = orthotopic liver transplantation