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Table 6 Uni- and multivariate analysis of risk factors for graft loss or death

From: Prevalence of human herpesviruses in biliary fluid and their association with biliary complications after liver transplantation

 

Univariate

 

Multivariate

 
 

Hazard ratio (95% CI)

p

Hazard ratio (95% CI)

p

HSV-1 positivity (bile)

2.34 (0.70–7,80)

0.17

  

HSV-1 positivity (serum)

0.43 (0.06–3.49)

0.39

  

EBV positivity (bile)

0.82 (0.28–2.38)

0.72

  

EBV positivity (serum)

2.18 (0.47–10.02)

0.32

  

CMV positivity (bile)

0.21 (0.29–1.58)

0.13

  

HHV-6 positivity (bile)

2.72 (1.25–5.90)

0.01

2.15 (0.94–4.95)

0.07

HHV-6 positivity (liver biopsy)

1.02 (0.30–3.46)

0.98

  

HHV-7 positivity (bile)

2.57 (1.14–5.78)

0.02

2.03 (0.81–5.12)

0.13

Valganciclovir at time of ERC

1.78 (0.97–3.26)

0.07

0.99 (0.48–2.07)

0.87

Time between LT and ERC [months]

0.93 (0.86–1.01)

0.08

0.94 (0.79–1.12)

0.27

NAS vs. AS/control

1.74 (0.99–3.05)

0.05

0.94 (0.79–1.12)

0.47

Recipient age, years

1.02 (0.97–1.07)

0.49

  

Donor age, years

1.02 (0.99–1.04)

0.18

  

MELD score at LT

0.94 (0.81–1.01)

0.12

  

Cold ischemia time

0.96 (0.83–1.11)

0.39

  
  1. AS, anastomotic biliary stricture, CMV cytomegalovirus, EBV Epstein-Barr virus, HHV human herpesvirus, ERC endoscopic retrograde cholangiopancreatography, HSV herpes simplex virus, LT liver transplantation, MELD model of end-stage liver disease, NAS non-anastomotic biliary stricture, VZV varicella-zoster virus