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Table 1 Classification criteria of clinical, CTE and GIUS evaluations

From: The potential role of CT enterography and gastrointestinal ultrasound in the evaluation of anti-tubercular therapy response of intestinal tuberculosis: a retrospective study

  Good response Partial response No response
Clinical evaluation Healing of all ulcers; or complete mucosal healinga of over 50% lesion area compared to the baseline colonoscopy; or mucosal healing of less than 50% lesion area, but over 50% decrease of hsCRP levels, plus over 50% symptom improvement [19] Improvements in some manifestations but cannot reach the “good response” criteria No improvement in any manifestations
CTE evaluation Lesion area decreased over 50% compared to previous CTE; or lesion area decreased less than 50%, plus a significant decrease in bowel wall thickness, less bowel wall enhancement and smaller lymph nodes Improvements in some manifestations but cannot reach the “good response” criteriab No improvement in any CTE manifestations
GIUS evaluation Lesion area decreased over 50% compared to previous GIUS; or lesion area decreased less than 50%, plus Limberg score decreased at least two grades [20] Improvements in some manifestations but cannot reach the “good response” criteria No improvement in any US manifestations
  1. aComplete mucosal healing is defined as completely normal appearance or residual fibrotic strictures of the mucosa
  2. bShrinkage of lymph nodes alone should not be considered as a sign of an effective therapeutic response