Good response | Partial response | No response | |
---|---|---|---|
Clinical evaluation | Healing of all ulcers; or complete mucosal healinga of over 50% lesion area compared to the baseline colonoscopy; or mucosal healing of less than 50% lesion area, but over 50% decrease of hsCRP levels, plus over 50% symptom improvement [19] | Improvements in some manifestations but cannot reach the “good response” criteria | No improvement in any manifestations |
CTE evaluation | Lesion area decreased over 50% compared to previous CTE; or lesion area decreased less than 50%, plus a significant decrease in bowel wall thickness, less bowel wall enhancement and smaller lymph nodes | Improvements in some manifestations but cannot reach the “good response” criteriab | No improvement in any CTE manifestations |
GIUS evaluation | Lesion area decreased over 50% compared to previous GIUS; or lesion area decreased less than 50%, plus Limberg score decreased at least two grades [20] | Improvements in some manifestations but cannot reach the “good response” criteria | No improvement in any US manifestations |