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Table 3 HLA-DQ data in relation to clinical and analytical features stratified by family history in CD

From: Influence of HLA on clinical and analytical features of pediatric celiac disease

  Sex
n = 463
Clinical Presentation
n = 463
Histological Damage
n = 458
Anti-TG2/EMA
n = 275
Anti-TG2 Levels
n = 172
M F Classical Non-Classical M3b + M3c Milder lesion Positive Negative ≥100 < 100
Family History HLA-DQ2.5 double dose 10
66.7%
5
33.3%
4
28.6%
10
71.4%
13
92.9%
1
7.1%
12
100%
0 6
75%
2
25%
Other HLA-DQ 3
42.9%
4
57.1%
3
37.5%
5
62.5%
8
100%
0 5
100%
0 3
60%
2
40%
Non-Family History HLA-DQ2.5
double dose
68
39.1%
106
60.9%
162
92.6%
13
7.4%
164
94.8%
9
5.2%
110
99.1%
1
0.9%
43
70.5%
18
29.5%
Other HLA-DQ 94
35.2%
173
64.8%
229
86.1%
37
13.9%
232
88.2%
31
11.8%
153
93.3%
11
6.7%
67
68.4%
31
31.6%