From: Influence of HLA on clinical and analytical features of pediatric celiac disease
Sex n = 463 | Clinical Presentation n = 463 | Histological Damage n = 458 | Anti-TG2/EMA n = 275 | Anti-TG2 Levels n = 172 | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
M | F | Classical | Non-Classical | M3b + M3c | Milder lesion | Positive | Negative | ≥100 | < 100 | ||
Family History | HLA-DQ2.5 double dose | 10 66.7% | 5 33.3% | 4 28.6% | 10 71.4% | 13 92.9% | 1 7.1% | 12 100% | 0 | 6 75% | 2 25% |
Other HLA-DQ | 3 42.9% | 4 57.1% | 3 37.5% | 5 62.5% | 8 100% | 0 | 5 100% | 0 | 3 60% | 2 40% | |
Non-Family History | HLA-DQ2.5 double dose | 68 39.1% | 106 60.9% | 162 92.6% | 13 7.4% | 164 94.8% | 9 5.2% | 110 99.1% | 1 0.9% | 43 70.5% | 18 29.5% |
Other HLA-DQ | 94 35.2% | 173 64.8% | 229 86.1% | 37 13.9% | 232 88.2% | 31 11.8% | 153 93.3% | 11 6.7% | 67 68.4% | 31 31.6% |